专利已注册

HEPATITIS B VIRUS CORE PROTEIN AND SURFACE ANTIGEN PROTEIN AND VACCINE COMPRISING THE SAME

Name: LaoBiz Laos Intellectual Property Database
Creator: LaoBiz

专利「HEPATITIS B VIRUS CORE PROTEIN AND SURFACE ANTIGEN PROTEIN AND VACCINE COMPRISING THE SAME」由 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 持有，当前状态为已注册，申请号 P/354。LaoBiz 老商通提供老挝知识产权信息检索与企业关联查询。

Patent “HEPATITIS B VIRUS CORE PROTEIN AND SURFACE ANTIGEN PROTEIN AND VACCINE COMPRISING THE SAME” is held by THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; status: 已注册. Search Laos IP records on LaoBiz.

申请号 P/354

申请日期 2013-09-19

申请人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

代理机构 CONCETTI-LAO CO., LTD

类别 A61K 39/29 · C12N 1/21 · C12N 15/09 · C12N 15/63 · C12N 5/10

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基础信息

类型: 专利
申请号: P/354
状态: 已注册
申请人: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
代理机构: CONCETTI-LAO CO., LTD
申请日期: 2013-09-19
注册号: P/354
公开/公告日: 2023-04-14
注册/授权日: 2023-04-11
届满日: 2033-09-19
国际分类: A61K 39/29 · C12N 1/21 · C12N 15/09 · C12N 15/63 · C12N 5/10
商品 / 服务: —

办理流程

根据当前状态动态标注

提交申请 2013-09-19
形式审查
实质审查
公开 2023-04-14
授权 2023-04-11

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ອຸປະກອນກໍາເນີດແກສມີເທນ ແລະ ວິທີກໍາເນີດແກສມີເທນ 已注册

摘要

ສະໜອງທີ່ນີ້ແມ່ນອາຊິດ ນີວກະເລໂອຕິດ ລໍາດັບ ການເຂົ້າລະຫັດ ໄວຣັດອັກເສບຕັບ B ໄວລັດ(HBV) ຫຼັກໂປຼຕີນ, ໜ້າພຽງຕົວຕ້ານໂປຼຕີນ, ພາກສ່ວນຍ່ອຍ ແລະ ການປະສົມປະສານ ເຫຼົ່ານີ້ເຊັ່ນດຽວກັບການກໍາມະພັນ/ບັນດາເວັກເຕີ ແລະ ວັກຊີນນັ້ນອະທິບາຍໂປຼຕີນລໍາດັບທີ່ກ່າວ. ວັກຊີນແມ່ນສາມາດກະຕຸ້ນການຕອບສະໜອງພູມຄຸ້ມກັນຢ່າງຕໍ່ພວງໜຶ່ງ ແລະ ໃນຕັບດ້ວຍເຮັດອອກໃຫ້ເຫັນທັງສອງແຊນລຸຍລາ ແລະ ຕົວຂອງແຫຼວສໍາລັບຮ່າງກາຍ. ຍັງສະໜອງແມ່ນບັນດາວິທີການສໍາລັບການປ້ອງກັນໂລກ ແລະ/ຫຼື ການຮັກສາໂລກ ພູມຕ້ານທານສ່ວນຕົວຕໍ່ HBV. ການປະສົມປະສານວັກຊີນອາດຍັງໄດ້ຖືກນໍາໃຊ້ສໍາລັບພາກສ່່ວນອອກແບບວັກຊິນສໍາລັບລະດັບສະເພາະຂອງພູມຕ້ານທານຕອບສະໜອງຫາການທ້າທາຍ HBV.

Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surfacea antigen proteins, fragments and combinations thereof as well as genetic constructs/vectors and vaccines that express said protein sequences. These vaccines are able to induce an immune response peripherally and in the liver by recruiting both cellular and humoral agents. Also provided are methods for prophylactically and/or therapeutically immunizing individuals against HBV. The combination Vaccine can also be used for particular design vaccines for particular levels of immune responses to HBV challenge.