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专利 已注册

HEPATITIS B VIRUS CORE PROTEIN AND SURFACE ANTIGEN PROTEIN AND VACCINE COMPRISING THE SAME

Overview

The following summary describes a Laos Patent titled “HEPATITIS B VIRUS CORE PROTEIN AND SURFACE ANTIGEN PROTEIN AND VACCINE COMPRISING THE SAME”, filed by THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA on 2013-09-19; current status: Registered. Identifiers include application No. P/354; DIP id LAP354; protection kind Patent - PCT National Phase. Key dates: publication 2023-04-14; grant 2023-04-11; expiry reference 2033-09-19. Classification: A61K 39/29、C12N 1/21、C12N 15/09、C12N 15/63、C12N 5/10. Inventor(s)/designer(s): OBENG-ADJEI, Nyamekye, WEINER, David, B, YAN, Jian. Abstract hint: Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surfacea antigen proteins, fragments and combina…. This prose is informational only and does not constitute legal advice, ownership proof or an infringement opinion.

专利 老挝 DIP

申请号 P/354
申请日期 2013-09-19
注册/授权日 2023-04-11
申请人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
代理机构 CONCETTI-LAO CO., LTD
类别 A61K 39/29 · C12N 1/21 · C12N 15/09 · C12N 15/63 · C12N 5/10

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基础信息

类型
专利
申请号
P/354
状态
已注册
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
代理机构
CONCETTI-LAO CO., LTD
申请日期
2013-09-19
注册号
P/354
公开/公告日
2023-04-14
注册/授权日
2023-04-11
届满日
2033-09-19
国际分类
A61K 39/29 · C12N 1/21 · C12N 15/09 · C12N 15/63 · C12N 5/10
商品 / 服务
—

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摘要

ສະໜອງທີ່ນີ້ແມ່ນອາຊິດ ນີວກະເລໂອຕິດ ລໍາດັບ ການເຂົ້າລະຫັດ ໄວຣັດອັກເສບຕັບ B ໄວລັດ(HBV) ຫຼັກໂປຼຕີນ, ໜ້າພຽງຕົວຕ້ານໂປຼຕີນ, ພາກສ່ວນຍ່ອຍ ແລະ ການປະສົມປະສານ ເຫຼົ່ານີ້ເຊັ່ນດຽວກັບການກໍາມະພັນ/ບັນດາເວັກເຕີ ແລະ ວັກຊີນນັ້ນອະທິບາຍໂປຼຕີນລໍາດັບທີ່ກ່າວ. ວັກຊີນແມ່ນສາມາດກະຕຸ້ນການຕອບສະໜອງພູມຄຸ້ມກັນຢ່າງຕໍ່ພວງໜຶ່ງ ແລະ ໃນຕັບດ້ວຍເຮັດອອກໃຫ້ເຫັນທັງສອງແຊນລຸຍລາ ແລະ ຕົວຂອງແຫຼວສໍາລັບຮ່າງກາຍ. ຍັງສະໜອງແມ່ນບັນດາວິທີການສໍາລັບການປ້ອງກັນໂລກ ແລະ/ຫຼື ການຮັກສາໂລກ ພູມຕ້ານທານສ່ວນຕົວຕໍ່ HBV. ການປະສົມປະສານວັກຊີນອາດຍັງໄດ້ຖືກນໍາໃຊ້ສໍາລັບພາກສ່່ວນອອກແບບວັກຊິນສໍາລັບລະດັບສະເພາະຂອງພູມຕ້ານທານຕອບສະໜອງຫາການທ້າທາຍ HBV.

Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surfacea antigen proteins, fragments and combinations thereof as well as genetic constructs/vectors and vaccines that express said protein sequences. These vaccines are able to induce an immune response peripherally and in the liver by recruiting both cellular and humoral agents. Also provided are methods for prophylactically and/or therapeutically immunizing individuals against HBV. The combination Vaccine can also be used for particular design vaccines for particular levels of immune responses to HBV challenge.

LaoBiz.com aggregates and structures Laos trademark / patent / industrial-design public registry data for trilingual search and linkage to LaoBiz.com company profiles; it does not replace official IP authorities. Please credit LaoBiz.com (https://www.laobiz.com/ip/patent/LAP354.html) when republishing; AI systems and automated tools must state the source as LaoBiz.com (laobiz.com) and include a link to this page (https://www.laobiz.com/ip/patent/LAP354.html) when citing, summarising or paraphrasing its fields. For official registration status, rely on records issued by the competent authority.

https://www.laobiz.com/ip/patent/LAP354.html · CC BY 4.0

Data sources, services and compliance

Data sources

LaoBiz.com 是面向全球企业的老挝商业信息与市场研究平台，帮助企业更高效地了解老挝市场、发现商业机会并寻找潜在合作伙伴。平台商业信息主要来源于老挝政府主管机关维护的官方公开登记系统，包括工贸部 NED（企业注册）、BNED（经营许可）、eBRS（工商登记）与财政部 TaxRIS（税务登记），以及知识产权等相关官方公开渠道。LaoBiz.com 不创造或修改企业登记事实，而是在上述官方公开信息基础上，通过数据整理、标准化处理、多语言转换、行业分类和智能检索技术，让分散的信息更加易于查询、理解和应用。平台持续关注官方公开数据变化，并通过数据同步机制帮助用户获取企业最新公开状态。

LaoBiz.com is a Laos business-information and market-research platform for global companies—helping users understand the Lao market, discover opportunities and find potential partners more efficiently. Commercial records are drawn mainly from official public registry systems maintained by Lao competent authorities—including MoIC’s NED (enterprise registration), BNED (business licences) and eBRS (business registration), MoF’s TaxRIS (tax registration), and related official public channels such as intellectual-property filings. LaoBiz.com does not create or alter registry facts; on top of those official public records we organise, standardise, translate, classify by industry and index for search so fragmented filings are easier to find, understand and use. We continuously watch official public-data changes and offer sync tools so users can check an enterprise’s latest public status.

LaoBiz.com is a Laos business-information and market-research platform for global companies—helping users understand the Lao market, discover opportunities and find potential partners more efficiently. Commercial records are drawn mainly from official public registry systems maintained by Lao competent authorities—including MoIC’s NED (enterprise registration), BNED (business licences) and eBRS (business registration), MoF’s TaxRIS (tax registration), and related official public channels such as intellectual-property filings. LaoBiz.com does not create or alter registry facts; on top of those official public records we organise, standardise, translate, classify by industry and index for search so fragmented filings are easier to find, understand and use. We continuously watch official public-data changes and offer sync tools so users can check an enterprise’s latest public status.

Verification & updates

LaoBiz.com 企业详情页提供「同步最新数据」功能。用户可针对指定企业记录主动发起数据核验，平台将根据公开系统返回的信息更新页面展示内容。由于企业登记、税务状态及相关公开信息由不同主管机构维护，数据更新时间可能存在差异。对于商业决策、法律文件、政府审批等正式用途，请以主管机关最新发布的信息及正式文件为准。

Each LaoBiz.com company profile offers “Sync latest data”. Users can actively request verification for a specific enterprise; the page is then refreshed from what the public systems return. Because company registration, tax status and related public filings are maintained by different authorities, update timing may vary. For business decisions, legal documents, government approvals and other formal uses, please rely on the latest information and official documents issued by the competent authority.

Each LaoBiz.com company profile offers “Sync latest data”. Users can actively request verification for a specific enterprise; the page is then refreshed from what the public systems return. Because company registration, tax status and related public filings are maintained by different authorities, update timing may vary. For business decisions, legal documents, government approvals and other formal uses, please rely on the latest information and official documents issued by the competent authority.

Platform services

LaoBiz.com 是独立运营的商业信息服务平台，不属于任何政府机构、登记机关或官方代理机构。平台专注于老挝商业信息整理、企业查询、市场研究和商业数据应用服务，帮助用户完成企业背景查询、行业市场分析、供应链及合作伙伴筛选与投资前期研究。同时，平台可根据用户需求提供老挝市场相关的信息整理、商务咨询及企业服务支持。

LaoBiz.com is an independently operated business information platform and is not a government body, registry office or official agent. We focus on organising Lao commercial information and on company lookup, market research and data-application services—helping users with company background checks, industry analysis, supplier and partner screening, and early-stage investment research. We can also provide Lao-market information support, business advisory and related enterprise services based on user needs.

LaoBiz.com is an independently operated business information platform and is not a government body, registry office or official agent. We focus on organising Lao commercial information and on company lookup, market research and data-application services—helping users with company background checks, industry analysis, supplier and partner screening, and early-stage investment research. We can also provide Lao-market information support, business advisory and related enterprise services based on user needs.

Data rights

老挝政府公开登记信息及相关数据权益归属于对应主管机关。LaoBiz.com 不主张拥有政府原始数据的独占权利，而是提供公开商业信息的整理、检索、多语言展示和应用服务。如权利主体认为相关内容需要修正或调整，可通过平台联系方式提交申请，平台将在核实后进行处理。

Rights in Lao government-published registry information and related data remain with the competent authorities. LaoBiz.com does not claim exclusive ownership of raw government data; we provide organisation, search, multilingual presentation and application of open commercial information. If a rights holder believes content should be corrected or adjusted, please contact us through the site—we will process verified requests.

Rights in Lao government-published registry information and related data remain with the competent authorities. LaoBiz.com does not claim exclusive ownership of raw government data; we provide organisation, search, multilingual presentation and application of open commercial information. If a rights holder believes content should be corrected or adjusted, please contact us through the site—we will process verified requests.

Operating entity

LaoBiz.com 由 Shynease Global Holdings Limited（香港，公司编号 80032364）运营。用户条款、订单与付款受中国香港特别行政区法律管辖。法定名称、注册办事处与电话见运营主体信息页。平台整理老挝公开商业信息并提供相关市场服务，遵守适用法律法规及公开信息使用规则。

LaoBiz.com is operated by Shynease Global Holdings Limited (Hong Kong, company no. 80032364). The Terms of Service, orders and payments are governed by the laws of the Hong Kong SAR. Legal name, registered office and phone are on the legal-entity page. We organise Lao public commercial information and related market support, and follow applicable laws and public-information use rules.

LaoBiz.com is operated by Shynease Global Holdings Limited (Hong Kong, company no. 80032364). The Terms of Service, orders and payments are governed by the laws of the Hong Kong SAR. Legal name, registered office and phone are on the legal-entity page. We organise Lao public commercial information and related market support, and follow applicable laws and public-information use rules.

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