OLIGONUCLEOTIDE CHELATE COMPLEXES
The following summary describes a Laos Patent titled “OLIGONUCLEOTIDE CHELATE COMPLEXES”, filed by REPLICOR INC. on 2011-08-18; current status: Registered. Identifiers include application No. P/239; DIP id LAP239; protection kind Patent - PCT National Phase. Key dates: publication 2023-03-24; grant 2023-03-24; expiry reference 2031-08-18. Classification: A61K 21/00、A61K 31/7088、A61K 31/712、A61K 31/7125、A61K 31/713、A61K 47/02. Inventor(s)/designer(s): Andrew VAILLANT, Michel BAZINET. Abstract hint: The present disclosure describes the broadly active chelation of divalent 2+ metal cations by any oligonucleotide(ON), re-gardless of size…. Status labels may change after office actions; refresh or consult primary DIP data before commercial decisions.
P/239
Mark
Key facts
- Type
- Patent
- App. no.
P/239- Status
- Registered
- Applicant
- REPLICOR INC.
- Agent
- Lao Trademark Agency
- Filing date
- 2011-08-18
- Reg. no.
P/239- Publication
- 2023-03-24
- Registration / grant
- 2023-03-24
- Expiry
- 2031-08-18
- Nice / IPC classes
- A61K 21/00 · A61K 31/7088 · A61K 31/712 · A61K 31/7125 · A61K 31/713 · A61K 47/02
- Goods / services
- —
Process
Steps follow the current public status-
Filed
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Formal examination
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Substantive examination
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Published
-
Granted
Related records
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Abstract
The present disclosure describes the broadly active chelation of divalent 2+ metal cations by any oligonucleotide(ON), re-gardless of size or modifiantion. This chelation effect is specific to cations which are divalent (or of higher valency) and results in the formation of oligonucleotide chelate complexes which do not behave like salts. It is described herein a novel composition of an ON chelate complex prepared using any ON and a divalent metal cation and methods for the suppression of anti-coagulation and or subcutaneous injection site reactions and or improved tolerability with oligonucleotides by the use of ON chelate complexes during oligonucleotide administration.
The present disclosure describes the broadly active chelation of divalent 2+ metal cations by any oligonucleotide(ON), re-gardless of size or modifiantion. This chelation effect is specific to cations which are divalent (or of higher valency) and results in the formation of oligonucleotide chelate complexes which do not behave like salts. It is described herein a novel composition of an ON chelate complex prepared using any ON and a divalent metal cation and methods for the suppression of anti-coagulation and or subcutaneous injection site reactions and or improved tolerability with oligonucleotides by the use of ON chelate complexes during oligonucleotide administration.
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